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Liquid Chromatography Mass Spectrometry LCMS-A11

Liquid Chromatography Mass Spectrometry LCMS-A11

Liquid Chromatography Mass Spectrometry LCMS-A11 features a flow rate range of 1 to 4000 µL/min, adjustable in 1.0 µL/min steps for precise control. It uses a triple quadrupole tandem mass spectrometer for accurate analysis. The system supports full loop, semi-loop, and microliter injection modes to suit various sample needs. It is equipped with E Spray biorthogonal electrospray ion source technology, offering high ionic yield and strong resistance to matrix effects. Our liquid chromatography mass spectrometry delivers high sensitivity in detecting sulfonamides in pork, pesticides in water, environmental pollutants, neonatal diseases, and vitamin D in serum.

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Flow Range 1 to 4000 µL/min, increments of 1.0 µL/min
Accuracy of Flow Rate ≤1%
Precision of Flow Rate ≤0.07% RSD
Maximum Pressure ≥18000 psi
Mobile Phase Selection Solvent selection valve allows any two of A, B, C, D as mobile phase
Vacuum Degasser Built-in; each pump degassed separately (A / B)
Delay Volume <50 µL (includes 35 µL mixer)
Gradient Modes Linear, concave, convex
Gradient Range 0 to 100%
Gradient Precision ≤0.15% RSD
Gradient Accuracy ±0.5% (absolute), 5% to 95%
Pressure Fluctuation <1% of system pressure or 5 bar (whichever greater)
Injection Modes Full loop, semi-loop, microliter
Injection Repeatability Full: <0.3% RSD; Semi: <0.5% RSD; Micro: <1.0% RSD
Sample Capacity Max 384 positions; ≥96 positions for 2 mL vials
Injection Range 1–500 µL (standard); 250, 1000, 2500 µL (optional)
Residue <0.05% (standard); <0.01% (extra rinse);
Sample Cooling 4℃±2℃ (min); Room temp to -3℃(max)
Temperature Control Range Room temp +5℃ to 90℃
Temperature Control Method Mobile phase preheating + forced air circulation
Maximum Column Capacity ≥5 columns, length ≥250 mm
Design Orthogonal vertical spray, anti-pollution, low background noise
Ion Source Gases 1 atomizing + 2 desolvation gases; flow rate set in software
Spray Voltage Max 6 kV; settable in software
Aux Heating Temp ≥700℃; settable in software
Exhaust Device Prevents backflow, reduces memory effect, protects pump and environment
Ion Interface Cone hole or capillary; capillary design requires 50 extra capillaries
Back-Blowing Design Reduces neutral molecule introduction
Interface Temp ≥110℃ to improve anti-pollution
Ion Transmission System 4-stage differential vacuum with multi-quadrupole focusing
Mass Analyzer Triple quadrupole
Quadrupole Material High-precision pure Mo; no need for extra temp control
Quadrupole Surface Gold-plated for anti-contamination
Quadrupole Structure Pre-rods before/after first; front pre-rod in second quadrupole
Collision Cell Linear or 90° curved; curved requires 3 years free cleaning commitment
Collision Gas High-purity nitrogen
Sensitivity ESI+: 1 pg reserpine, S/N≥300,000:1; ESI-: 1 pg chloramphenicol, S/N≥300,000:1
Quantitative Reproducibility Reserpine & Chloramphenicol: RSD ≤5% (6 injections)
Quadrupole Resolution 0.4 to 3.0 amu adjustable
Mass Stability ≤0.1 amu/24h
Scan Speed ≥20,000 amu/s
Min Scan Step 0.02 amu
Dynamic Range 6 orders of magnitude
MRM Channels ≥30,000 MRM groups per injection with no sensitivity loss
Min Dwell Time 1 ms
MS/MS Switch Time ≤1 s
Detector Type Electron multiplier tube
Detection Method Pulse counting for low concentration reproducibility
Vacuum System Configuration Mechanical + turbomolecular pump, differential exhaust, auto power-off
Mechanical Pump Speed 65 m³/h
Turbo Pump Speed 50 / 400 / 500 L/s
Workstation Software Platform Windows XP and above
Automation Calibration, instrument monitoring
Power Supply (220±20) V AC,10A,50 Hz
Dimension 750 × 660 × 670 mm
Packaging Dimension 940 × 830 × 600 mm
Net Weight 48 Kg
Gross Weight 68 Kg
  • Step scan ion transmission

  • Low-noise pulse counting detection

  • Superior stability

  • High sensitivity

  • User-friendly design

Liquid Chromatography Mass Spectrometry LCMS-A11 detects sulfonamides in pork, pesticides in water, pollutants, neonatal diseases, and vitamin D levels in serum with high sensitivity.

Accessories Name

Quantity

Ultra-High Pressure Gradient Pump

1 pc

Automatic Sample Injector

1 pc

Column Oven

1 pc

ESI Ion Source

1 pc

Vacuum Interface and Ion Transmission System

1 pc

Mass Analysis System

1 pc

Detector

1 pc

Vacuum System

1 pc

Workstation Software

1 pc

Accessories Name

Quantity

Computer System

1 pc

AC Regulated Power Supply

1 pc

Laser Printer

1 pc

Nitrogen Generator

1 pc

Bottle of High-Purity Nitrogen (including gas pressure reducing valve)

1 pc

 Liquid Chromatography Mass Spectrometry LCMS-A11 | Flow Range: 1 to 4000 µL/min, increments of 1.0 µL/min | Accuracy of Flow Rate: ≤1%
Liquid Chromatography Mass Spectrometry LCMS-A11 | Step scan ion transmission | Low-noise pulse counting detection

Models of Liquid Chromatography Mass Spectrometry (LCMS)

Labtron liquid chromatography mass spectrometry (LCMS) offer increased detection and quantification limits with improved repeatability, accuracy, and selectivity. They have powerful ion sources, cutting-edge ion transmission systems, and extensive technique libraries. They are designed to operate reliably thanks to safety interlocks, sophisticated batch processing, and automated tuning. These devices provide dual ion sources for flexible compound analysis. Our LCMS systems provide an intuitive workstation and pulse detection for efficient operation and best outcomes.

Liquid Chromatography Mass Spectrometry LCMS-310

Liquid Chromatography Mass Spectrometry LCMS-310

  • Mass Range : m/z 2 to 2,000
  • Resolution : R < 0.7 u FWHM and adjustable to 0.5 u
  • Scan Speed : ≥2,0000 amu/s
  • Ionization Switching Time : 20 ms
Liquid Chromatography Mass Spectrometry LCMS-A10

Liquid Chromatography Mass Spectrometry LCMS-A10

  • Flow Range : 1 to 4,000 µL/min
  • Accuracy Of Flow Rate : ≤1%
  • Precision Of Flow Rate : ≤ 0.075% RSD
  • Maximum Pressure : ≥ 18,850 psi

Liquid Chromatography Mass Spectrometry LCMS-A11 FAQ's
  • Labtron Liquid Chromatography Mass Spectrometry is widely used for detecting and analyzing trace amounts of substances in complex samples. It plays a crucial role in food safety, environmental monitoring, clinical diagnostics, and pharmaceutical research. For example, it can detect sulfonamides in pork, pesticides in water, pollutants in soil, and even vitamin D levels in blood serum. Its high sensitivity and accuracy make it ideal for identifying very small quantities of chemicals, which is essential for quality control and public health safety.

  • Labtron system combines high-performance liquid chromatography with a triple quadrupole mass spectrometer to achieve exceptional precision. The use of advanced technologies like step scan ion transmission, low-noise pulse counting detection, and a gold-plated quadrupole structure ensures minimal background interference and high signal clarity. Additionally, its E Spray biorthogonal electrospray ion source provides strong resistance to matrix effects, which helps maintain consistent accuracy even when analyzing complex or dirty samples.

  • Labtron system is designed for flexibility, allowing users to choose from full loop, semi-loop, or microliter injection modes based on the sample type and volume. It supports a wide range of flow rates and has a highly accurate and repeatable injection system, ensuring reliable results with minimal sample residue. This makes it suitable for both routine laboratory testing and advanced research where different injection techniques may be needed depending on the sample’s characteristics.

  • Labtron uses a robust design with a four-stage differential vacuum and multi-quadrupole focusing for stable ion transmission. It also features a vacuum system with both mechanical and turbomolecular pumps, ensuring consistent pressure and protection against backflow. Features like preheated mobile phase lines, anti-pollution spray design, and gold-plated components reduce contamination risks and extend maintenance intervals. These aspects ensure the instrument remains stable and reliable even during long-term, high-throughput operations.

  • Yes, Labtron Liquid Chromatography Mass Spectrometry is suitable for use in regulated environments, including clinical laboratories. Its automation features such as built-in calibration, instrument monitoring, and temperature control support compliance with strict quality standards. The system is designed for high-throughput applications with excellent reproducibility, making it reliable for diagnosing neonatal diseases or monitoring therapeutic drug levels. Its ability to detect extremely low concentrations with high precision is particularly important in clinical and pharmaceutical settings.

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Email: info@labtron.com

WhatsApp: +44 73 4441 2688

Phone: +44 2080 043608

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Labtron Equipment Ltd., Quatro House, Lyon Way, Camberley, Surrey GU16 7ER United Kingdom

Email: info@labtron.com Whatsapp: +44 73 4441 2688 Phone: +44 2080 043608

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